Thoughts on obesity.

Thoughts on Obesity and Brain Glucose

Homeostatic control of brain metabolism is essential for neuronal activity. Jais et al., (2016) report that reduced brain glucose uptake elicited by a high-fat diet self-corrects by the recruitment of peripheral, VEGF-producing macrophages to the blood-brain barrier. Their findings further suggest that restoring brain glucose availability might help protect from cognitive impairment in Alzheime...

Recent Advances in Clinical Practice New Thoughts on Managing Obesity

Correspondence to: Professor P Kopelman, Queen Mary’s School of Medicine and Dentistry, Turner St, London E1 2AD, UK; [email protected] _________________________ BACKGROUND: OBESITY AS A PUBLIC HEALTH PROBLEM Obesity is defined as a body mass index (BMI) of 30 kg/m or more, where a person’s BMI is defined as their weight in kg divided by the square of their height in metres. Overweight is...

Thoughts on Social Design

Thoughts on the Bulletin.

Because daguerreotype photographs are usually reversed laterally from actuality, images of W.T.G. Morton falsely suggest that he sometimes changed the side of the part in his hair. Because of daguerreotype image reversal, a statue of Apollo in the Ether Dome at the Massachusetts General Hospital appears to have been moved for the 50th anniversary of Ether Day. Ether anesthesia was announced in ...

Thoughts on scale

I begin with a metaphor to characterize the challenges that authors and readers face when confronting issues of scale. Consider the ways that map makers use insets—devices that allow for a focus on particular areas, while situating those areas within the larger whole. The use of insets allows for characterizations at two orders of grain size. Now imagine a map of the world containing four inset...